Welcome to Kelvin Lee's Research Group


Our academic home is the Department of Chemical and Biomolecular Engineering and our research laboratories are at the Delaware Biotechnology Institute at the University of Delaware. Our research infrastructure includes modern technologies and techniques for molecular biology, high throughput gene sequencing and gene expression monitoring, proteomics, and cell biology. We work closely with our colleagues from Chemical Engineering, Plant and Soil Sciences, Biology, Chemistry and Biochemistry, and Materials Science and Engineering. Moreover, we have ongoing collaborations with a number of corporate partners and clinicians as well as academics around the world.

Delaware Biotechnology Insititute


The research laboratory solves problems by working at the molecular scale. The types of problems we work on are dictated in part by student interest but fall into the following general categories: proteomics, biomedical engineering, biomolecular & bioprocess engineering, systems biology, and energy & the environment. More specifically, our current (2012) research projects address the following specific issues:

  1. Improving productivity and product quality of biopharmaceuticals based on the CHO genome.
  2. Improving productivity of biopharmaceuticals by enhancing bacterial secretion.
  3. Building in vitro models of the blood-brain barrier to facilitate drug development.
  4. Improving the diagnosis and treatment of Alzheimer's disease.
  5. Developing new methods to make next generation biofuels.
  6. Understanding microbial communities in the environment.

Brain Endothelial Cells: Stained for the tight junction protein,
Green - Occludin, Blue - Nuclei


Our research team is an enthusiastic group of undergraduate and graduate students, postdoctoral scientists and research associates, as well as professional laboratory staff. We meet regularly as a group and disseminate our findings in a number of regular meetings (American Institute of Chemical Engineering, American Chemical Society BIOT Division, American Society for Mass Spectrometry, International Conference on Alzheimer's Disease, Biochemical Engineering, Cell Culture Engineering, and others). We are always looking for bright, motivated new people to join our team.

June 2013 - Group Picnic

People (front row, left to right): Kelvin, Wen, Pei, Stephanie, Allison, Leila, Amalie, Nora, Lie, Anna, Kristin;
(back row): Phillip, Tom, Jen, Diane, Jay, Ben, Shuyu, Bryan, JongYoun, Yeajin