BS: Life Sciences, Zhejiang University, China
PhD: Cellular and Molecular Biology, University of Wisconsin Madison
Research Project: Studying double-strand break (DSB) repair genes in CHO cells
The frequent chromosomal rearrangement (genome instability) in CHO cells is a double-edged sword for industrial application. It might be the cause of their easy adaption to difference conditions, but also the cause of production instability.
Our hypothesis is that the deficient double-strand break (DSB) repair leads to genome instability. We develop assays to identify the genes that cause DSB repair deficient and the genome instability in CHO cells.